The CAT Tails are capable of sending or receiving signals, just like an analog snake. You can use gender turnarounds to send and receive. When sending mixed signals a high quality CAT cable is encouraged.
The short answer is no. But in order to use phantom power and to minimize noise, we strongly suggest you use properly shielded cable. You can check if your cable is shielded by checking for continuity on the RJ45 jack using a multi-meter. Still not sure? Just purchase SuperCAT and you know you'll be covered.
While the CAT Box will work with any console on the market, it is important to note that it does not do any D/A conversion. The beauty of the CAT Box is that it sends analog audio over lightweight CAT cable, no conversion required. Hook directly up to your XLR connections and let CAT Box do the rest.